20 Best Enzymatic Cleaner For Dog Urine (2023 Updated)

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Enzymatic cleaners are designed to break down the proteins in dog urine, making it easier to remove the stain and odor. These cleaners are often used in conjunction with other cleaning products, such as vinegar or baking soda, to further remove the stain and odor.

20 Best Enzymatic Cleaner For Dog Urine

Product Image Product Name Features Price

Bubbas Super Strength Commercial Enzyme Cleaner – Pet Odor Eliminator

  • Maintains Your Carpets And Floors, Plus Prevents Re-Marking By Your Pets
  • Guard Against Pet Odor
  • The Secret To Removing Pet Stains And Odors

Pet Stain & Odor Miracle – Enzyme Cleaner for Dog and Cat Urine, Feces, Vomit,

  • 32 Fl Oz

Bubbas Super Strength Commercial Enzyme Cleaner – Pet Odor Eliminator | Enzymatic …

  • Maintains Your Carpets And Floors, Plus Prevents Re-Marking By Your Pets
  • -Save Your Carpet & Flooring
  • -Guard Against Pet Odor

TriNova Natural Pet Stain and Odor Remover Eliminator Advanced Enzyme Cleaner Spray

  • Uses an advanced blend of natural enzymes that tackle stains and odors at their root to clean and neutralize
  • The enzymes work to break down stains, drying out and disintegrating when they’re finished to restore your carpet to like-new condition

Angry Orange Bio-Enzyme Pet Stain & Odor Remover, 32-oz Bottle

  • 32 Fl Oz (Pack Of 1)

Angry Orange Enzyme Stain Cleaner & Pet Odor Eliminator, 32oz

  • 32 Fl Oz (Pack Of 1)

Nature's Miracle Enzymatic Formula Stain & Odor Remover – 1.00 Gal

  • Works on old and deep-set stains and odors.
  • For use on carpets, floors, furniture, clothing, and all pet living areas.
  • Perfect for spot cleaning and removing surface stains and odors.

Simple Solution Extreme Urine Destroyer (32 fl oz)

  • 32 oz

Nature's Miracle Urine Destroyer 32 oz

  • 32 oz

Woolite Pet Urine Eliminator +Enzyme Action – 22 fl oz

  • Enzyme Cleaning Action
  • Eliminates tough pet stains and odors
  • Continues to work 24 hours to completely remove the stain to the carpet backing

Nature's Miracle Urine Destroyer Plus Squeeze Jar Dogs – 32 fl oz

  • 32 oz

Nature's Miracle Urine Destroyer Plus – 1 Gal

  • 128 oz

Simple Solution Urine Destroyer Enzymatic Cleaner | Pet Stain and Odour Remover with Pro-Bacteria Cleaning Power – 1 Ltrs

  • ELIMINATE STAINS – Simple Solution’s enzymatic cleaner technology lifts urine stains leaving your carpet stain and odour free.

Angry Orange Enzyme Cleaner & Pet Stain Remover Spray – 32oz Pet Odor Eliminator for Home, Carpet, and Floor – Cat and Dog Urine Destroyer (Fresh

  • 32oz Pet Odor Eliminator for Home, Carpet, and Floor.
  • Cat and Dog Urine Destroyer (Fresh Citrus Scent) Warning: Do not apply product directly to your pet or use in a diffuser or steam cleaner.

Pee Pee Stain & Odor Eliminator – 32 fl oz

  • This product adds a great value
  • Product is highly durable and very easy to use
  • This product is manufactured in China

Nature's Miracle Stain & Odor Remover (1 Gallon)

  • Tough on urine, feces, vomit, drool and other organic stains and odors
  • For use on carpets, hard floors, furniture, fabrics and more

Urine Gone! Stain and Odor Eliminator Refill – 24 fl oz bottle

  • Powerful enzyme action
  • Cleans & deodorizes
  • Amazingly effective and easy to use

Simple Green Bio Dog Stain & Odor Remover – 1.0 Gal

  • 1 Gal

Nature's Miracle Stain & Odor Remover (32 oz)

  • Works to remove pet stains and odors
  • Freshens with a light citrus scent
  • Bacteria-based formula produces enzymes when it comes in contact with Bio material to help remove organic stains and odors
Bubbas Super Strength Commercial Enzyme Cleaner – Pet Odor Eliminator
  • Maintains Your Carpets And Floors, Plus Prevents Re-Marking By Your Pets
  • Guard Against Pet Odor
  • The Secret To Removing Pet Stains And Odors
Pet Stain & Odor Miracle – Enzyme Cleaner for Dog and Cat Urine, Feces, Vomit,
  • 32 Fl Oz
Bubbas Super Strength Commercial Enzyme Cleaner – Pet Odor Eliminator | Enzymatic …
  • Maintains Your Carpets And Floors, Plus Prevents Re-Marking By Your Pets
  • -Save Your Carpet & Flooring
  • -Guard Against Pet Odor
TriNova Natural Pet Stain and Odor Remover Eliminator Advanced Enzyme Cleaner Spray
  • Uses an advanced blend of natural enzymes that tackle stains and odors at their root to clean and neutralize
  • The enzymes work to break down stains, drying out and disintegrating when they’re finished to restore your carpet to like-new condition
Angry Orange Bio-Enzyme Pet Stain & Odor Remover, 32-oz Bottle
  • 32 Fl Oz (Pack Of 1)
Angry Orange Enzyme Stain Cleaner & Pet Odor Eliminator, 32oz
  • 32 Fl Oz (Pack Of 1)
Nature's Miracle Enzymatic Formula Stain & Odor Remover – 1.00 Gal
  • Works on old and deep-set stains and odors.
  • For use on carpets, floors, furniture, clothing, and all pet living areas.
  • Perfect for spot cleaning and removing surface stains and odors.
Simple Solution Extreme Urine Destroyer (32 fl oz)
  • 32 oz
Nature's Miracle Urine Destroyer 32 oz
  • 32 oz
Woolite Pet Urine Eliminator +Enzyme Action – 22 fl oz
  • Enzyme Cleaning Action
  • Eliminates tough pet stains and odors
  • Continues to work 24 hours to completely remove the stain to the carpet backing
Nature's Miracle Urine Destroyer Plus Squeeze Jar Dogs – 32 fl oz
  • 32 oz
Nature's Miracle Urine Destroyer Plus – 1 Gal
  • 128 oz
Simple Solution Urine Destroyer Enzymatic Cleaner | Pet Stain and Odour Remover with Pro-Bacteria Cleaning Power – 1 Ltrs
  • ELIMINATE STAINS – Simple Solution’s enzymatic cleaner technology lifts urine stains leaving your carpet stain and odour free.
Angry Orange Enzyme Cleaner & Pet Stain Remover Spray – 32oz Pet Odor Eliminator for Home, Carpet, and Floor – Cat and Dog Urine Destroyer (Fresh
  • 32oz Pet Odor Eliminator for Home, Carpet, and Floor.
  • Cat and Dog Urine Destroyer (Fresh Citrus Scent) Warning: Do not apply product directly to your pet or use in a diffuser or steam cleaner.
Pee Pee Stain & Odor Eliminator – 32 fl oz
  • This product adds a great value
  • Product is highly durable and very easy to use
  • This product is manufactured in China
Nature's Miracle Stain & Odor Remover (1 Gallon)
  • Tough on urine, feces, vomit, drool and other organic stains and odors
  • For use on carpets, hard floors, furniture, fabrics and more
Urine Gone! Stain and Odor Eliminator Refill – 24 fl oz bottle
  • Powerful enzyme action
  • Cleans & deodorizes
  • Amazingly effective and easy to use
Simple Green Bio Dog Stain & Odor Remover – 1.0 Gal
  • 1 Gal
Nature's Miracle Stain & Odor Remover (32 oz)
  • Works to remove pet stains and odors
  • Freshens with a light citrus scent
  • Bacteria-based formula produces enzymes when it comes in contact with Bio material to help remove organic stains and odors

1. Bubbas Super Strength Commercial Enzyme Cleaner – Pet Odor Eliminator

Bubbas Super Strength Commercial Enzyme Cleaner - Pet Odor Eliminator

  • Maintains Your Carpets And Floors, Plus Prevents Re-Marking By Your Pets
  • Guard Against Pet Odor
  • The Secret To Removing Pet Stains And Odors

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Product Details

Specifications

Details
Is Discontinued By Manufacturer No
Product Dimensions 6 x 6 x 12 inches; 8 Pounds
Country of Origin USA
Item Package Dimensions L x W x H 11.73 x 6.1 x 6.02 inches
Item Dimensions LxWxH 6 x 6 x 12 inches
Contains Liquid Contents Yes

2. Pet Stain & Odor Miracle – Enzyme Cleaner for Dog and Cat Urine, Feces, Vomit,

Pet Stain & Odor Miracle - Enzyme Cleaner for Dog and Cat Urine, Feces, Vomit,

  • 32 Fl Oz

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Product Details

Specifications

Details
Package Dimensions 10.7 x 4.9 x 2.9 inches
Is Discontinued By Manufacturer No

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abqgram45
Melissa H
msbohemia

3. Bubbas Super Strength Commercial Enzyme Cleaner – Pet Odor Eliminator | Enzymatic …

Bubbas Super Strength Commercial Enzyme Cleaner - Pet Odor Eliminator | Enzymatic ...

  • Maintains Your Carpets And Floors, Plus Prevents Re-Marking By Your Pets
  • -Save Your Carpet & Flooring
  • -Guard Against Pet Odor
  • The Secret To Removing Pet Stains And Odors
  • Order Now. Always Be Prepared

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Sold By Price
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eBay – 2bfairshop
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Fleapacks.com

Product Details

Specifications

Details
Is Discontinued By Manufacturer No
Product Dimensions 5 x 2 x 10 inches; 2.2 Pounds
Item Package Dimensions L x W x H 11.26 x 4.65 x 2.76 inches
Item Dimensions LxWxH 5 x 2 x 10 inches
Target Audience Keyword Cats, House-cats, Dogs
Contains Liquid Contents Yes

4. TriNova Natural Pet Stain and Odor Remover Eliminator Advanced Enzyme Cleaner Spray

TriNova Natural Pet Stain and Odor Remover Eliminator Advanced Enzyme Cleaner Spray

  • Uses an advanced blend of natural enzymes that tackle stains and odors at their root to clean and neutralize
  • The enzymes work to break down stains, drying out and disintegrating when they’re finished to restore your carpet to like-new condition
  • Designed to work effectively on a wide range of surfaces, including carpet, rugs, upholstery and more

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Product Details

Specifications

Details
Odor Eliminator Yes
Scent Neutral
Application Method Pump spray
Deodorizing Yes
Prevents Resoiling Yes
Form Spray
Maximum Coverage Area (Sq. Feet) 100
Safe for Upholstery Yes
Package Quantity 1
Removes Pet Stains Yes

Reviews From Real Customers

sarsamson0418
zm1014
kaley1996

5. Angry Orange Bio-Enzyme Pet Stain & Odor Remover, 32-oz Bottle

Angry Orange Bio-Enzyme Pet Stain & Odor Remover, 32-oz Bottle

  • 32 Fl Oz (Pack Of 1)

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Angry Orange

Product Details

Specifications

Details
Is Discontinued By Manufacturer No
Package Dimensions 11.46 x 4.69 x 3.39 inches; 2.29 Pounds
Formulation Type Concentrated
Specific Uses For Product Organic, Fights Odor, Stain Remover, Natural

Reviews From Real Customers

Frustrates
Michelle D.

6. Angry Orange Enzyme Stain Cleaner & Pet Odor Eliminator, 32oz

Angry Orange Enzyme Stain Cleaner & Pet Odor Eliminator, 32oz

  • 32 Fl Oz (Pack Of 1)

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Product Details

Specifications

Details
Animal Type All Pets
Product Form Liquid
Product Type Enzyme Stain And Odor Remover
Number in Package 1 pk
Container Size 32 oz

7. Natural Care + Enzymatic Cleaner, All Natural, Urine Stain + Odor Destroyer – 32 fl oz

Natural Care + Enzymatic Cleaner, All Natural, Urine Stain + Odor Destroyer - 32 fl oz

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Product Details

Specifications

Details
Units in Package 1
Unit Size 32 fl oz
Directions Before Use: Remove excess solid or liquid waste. Shake well and test for colorfastness on a hidden area. Do not use on wool or leather surfaces. Saturate the soiled area when treating carpet, cover twice the size of the mess and be sure to saturate the carpet backing and padding. Wait 10 or more minutes for the enzymes and Pro-Bacteria to break down the organic proteins. Blot excess moisture with a color-safe cloth. Allow the area to dry naturally, which may take 24-48 hours. When dry, the stain and odor will disappear. Guaranteed. If the area is dry but an odor persists, the odor source was not completely penetrated Re-treat and be sure to completely saturate the soiled area to penetrate the odor source. Carpet Cleaning Machines: Pretreat heavily soiled areas using the above directions. Add 4 fl. Oz. To one gallon of shampoo/water. To enhance the machine’s spot cleaning power.
Ingredients Purified Water, Natural Non-Pathogenic Bacteria, Denatured Ethanol, Natural Enzymes and Fragrance.
Warnings Avoid eye contact, product may irritate eyes. In case of eye contact, flush thoroughly with water for 15 minutes. Keep this and all cleaning products out of reach of children and animals.

8. Nature’s Miracle Enzymatic Formula Stain & Odor Remover – 1.00 Gal

Nature's Miracle Enzymatic Formula Stain & Odor Remover - 1.00 Gal

  • Works on old and deep-set stains and odors.
  • For use on carpets, floors, furniture, clothing, and all pet living areas.
  • Perfect for spot cleaning and removing surface stains and odors.

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Lowe’s

Product Details

Specifications

Details
Scent No
Product Form Liquid
Number in Package 1 pk
Application Multi-Purpose
Container Size 1 gal

Reviews From Real Customers

ChelleH
molly.k
Teri

9. Simple Solution Extreme Urine Destroyer (32 fl oz)

Simple Solution Extreme Urine Destroyer (32 fl oz)

  • 32 oz

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PBS Animal Health

Product Details

Specifications

Details
Global Brand License Simple Solution
Multipack Quantity 1
Recommended Surface Carpet
Animal Type Cats and Dogs
Assembled Product Weight 1.63 oz

10. Nature’s Miracle Urine Destroyer 32 oz

Nature's Miracle Urine Destroyer 32 oz

  • 32 oz

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PetMountain.com

Product Details

Specifications

Details
Animal Type Dog
Product Type Urine Eliminator
Container Size 32 oz
Brand Name Nature’s Miracle

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NancyDrew50
JaneB

11. Woolite Pet Urine Eliminator +Enzyme Action – 22 fl oz

Woolite Pet Urine Eliminator +Enzyme Action - 22 fl oz

  • Enzyme Cleaning Action
  • Eliminates tough pet stains and odors
  • Continues to work 24 hours to completely remove the stain to the carpet backing
  • Patented odor technology eliminates tough pet odors

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Frankfort Hardware
Shell Lumber and Hardware

Product Details

Specifications

Details
Units in Package 1
Unit Size 22 fl oz
Directions Before Cleaning: remove solid residue and blot excess liquid with a clean, colorfast, absorbent cloth. Test for colorfastness on a hidden area. If color is affected, do not use this product. Before using this product on upholstery, look for a manufacturer’s cleanability code tag. Use on upholstery coded WS or W. Do not use on upholstery coded X or S. Do not use on velvet, silk, vinyl or leather upholstery. How to Use: remove solid particles or excess liquid. Shake well, turn nozzle to spray position and saturate soiled and surrounding area; let sit for 5-10 minutes to penetrate stain. Blot with dry, color-safe cloth to remove stain and absorb as much as possible; rinse and repeat as needed (for heavily soiled areas, maximize enzyme action by covering with a clean, damp cloth so the area remains moist for 12-24 hours. Uncover to dry). Stay off and keep kids & pets off cleaned area until dry and vacuumed. For Best Results: treat stains immediately. Stains allowed to dry and set can cause bleaching and may be difficult to remove. To more effectively clean stains such as pet urine, a larger area around the stain should be treated and cleaned.
Warnings Caution: Avoid eye contact. In case of eye contact, flush thoroughly with water for at least 15 minutes. Get medical attention if irritation develops or persists. Keep out of reach of children & pets. This product does not contain phosphates. Contains no harsh chemicals or solvents. Do not expose to heat or store at temperatures above 120 degrees F.

Reviews From Real Customers

Dave
bissell.com
AlexFortune

12. Nature’s Miracle Urine Destroyer Plus Squeeze Jar Dogs – 32 fl oz

Nature's Miracle Urine Destroyer Plus Squeeze Jar Dogs - 32 fl oz

  • 32 oz

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Product Details

Specifications

Details
Primary Brand Nature’s Miracle
Scented No
Volume 32 FZ

13. Nature’s Miracle Urine Destroyer Plus – 1 Gal

Nature's Miracle Urine Destroyer Plus - 1 Gal

  • 128 oz

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Product Details

Specifications

Details
Primary Brand Nature’s Miracle
Scented No
Volume 128 FZ

14. Simple Solution Urine Destroyer Enzymatic Cleaner | Pet Stain and Odour Remover with Pro-Bacteria Cleaning Power – 1 Ltrs

Simple Solution Urine Destroyer Enzymatic Cleaner | Pet Stain and Odour Remover with Pro-Bacteria Cleaning Power - 1 Ltrs

  • ELIMINATE STAINS – Simple Solution’s enzymatic cleaner technology lifts urine stains leaving your carpet stain and odour free.
  • CARPET SAFE – Certified by the wool safe Institute, our Pet Urine Destroyer is safe to use on all colourfast carpets when used as directed.
  • SAFE FOR THE HOME – Simple Solution pet urine remover is safe for use around pets and your household when used as directed.

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Details
binding Misc

15. Angry Orange Enzyme Cleaner & Pet Stain Remover Spray – 32oz Pet Odor Eliminator for Home, Carpet, and Floor – Cat and Dog Urine Destroyer (Fresh

Angry Orange Enzyme Cleaner & Pet Stain Remover Spray - 32oz Pet Odor Eliminator for Home, Carpet, and Floor - Cat and Dog Urine Destroyer (Fresh

  • 32oz Pet Odor Eliminator for Home, Carpet, and Floor.
  • Cat and Dog Urine Destroyer (Fresh Citrus Scent) Warning: Do not apply product directly to your pet or use in a diffuser or steam cleaner.

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Petzome

Product Details

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dawn

16. Pee Pee Stain & Odor Eliminator – 32 fl oz

Pee Pee Stain & Odor Eliminator - 32 fl oz

  • This product adds a great value
  • Product is highly durable and very easy to use
  • This product is manufactured in China

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Product Details

Specifications

Details
Units in Package 1
Unit Size 32 fl oz
Directions 1. Before use, apply a small amount of product to an inconspicuous area to test for colorfastness. If color is removed, do not use on those surfaces. 2. Remove excess stain and odor causing material. 3. Shake bottle well. 4. Spray entire stained area with Pee-Pee Stain & Odor Eliminator. Do not dilute. Wait five minutes then wipe away stain with a clean cloth. If treating carpet, be sure to use enough to reach the carpet backing and padding. Allow the product to penetrate into the surface then blot excess product with clean cloth. 5. Dry naturally. Once the area is completely dry, any residual odor will disappear. If odor persists, repeat as needed. Laundry Pre-Wash: Apply to soiled area and allow to penetrate stain for five minutes. Wash as recommended. Carpet Cleaning Machines: Dilute Pee-Pee Stain & Odor Eliminator 50/50 with water. Product can be used to clean litter boxes, birdcages and all pet living areas.
Ingredients Water, Cleaning Solvent, Surfactant, Chelating Agent, Whitening Enhancer, ph Adjuster, Odor Neutralizer, Preservative.
Warnings Avoid contact with eyes. In case of eye contact, flush eye thoroughly water. Keep this and all cleaning products out of the reach of children and animals. Do not spray directly on animal.

Reviews From Real Customers

meowmeow
Vickie
Cleocatra

17. Nature’s Miracle Stain & Odor Remover (1 Gallon)

Nature's Miracle Stain & Odor Remover (1 Gallon)

  • Tough on urine, feces, vomit, drool and other organic stains and odors
  • For use on carpets, hard floors, furniture, fabrics and more
  • Enzymatic formula
  • Light, citrus scent
  • Safe for pets and home, when used as directed

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McGuckin Hardware

Product Details

Specifications

Details
Weight 8 lb

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kristen n.m
liisa.m
lauren.g

18. Urine Gone! Stain and Odor Eliminator Refill – 24 fl oz bottle

Urine Gone! Stain and Odor Eliminator Refill - 24 fl oz bottle

  • Powerful enzyme action
  • Cleans & deodorizes
  • Amazingly effective and easy to use
  • Works immediately with pet or people accidents

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Product Details

Specifications

Details
Units in Package 1
Unit Size 24 fl oz
Directions Directions for Use on Wet and Dry Stains: 1. Remove any excess wetness or solids from the stained area. Soak up or blot up excess matter with paper towel. 2. Completely saturate stained area with Urine Gone. For carpet stains, ensure padding is also saturated. Urine Gone must soak all of the affected area to eliminate the stain and smell. Do not blot up Urine Gone. It must remain wet in order to work. Do not shampoo carpet stains before using Urine Gone as it will interfere with the enzyme. 3. If a colored stain is noticeable on carpets, fabric or upholstery, rub Urine Gone into the stained area while spraying. This assists in removing the visible mark of the stain. 4. Let completely air dry. 5. Blot with a damp towel to remove any surface residue after stained area is totally dry. 6. If stain is still noticeable, repeat until all evidence of stain is gone. Find the Stain: Simply darken room and use the stain detective black light to show the urine messes. Check carpets, mattresses, furniture, bathrooms, walls and floors. The stains will glow so that you don’t miss any. Then use Urine Gone to soak the entire stain.
Ingredients Water, Soya Morpholinium Ethosulfate, Cocamidopropyl Betaine, Sodium Bicarbonate, Proteolytic Enzymes, EDTA, Fragrance.
Warnings Never use directly on people, animals or in pet litter. Keep out of reach of children. Do not ingest. Keep out of eyes and off skin. If any irritation develops, contact physician immediately.

19. Simple Green Bio Dog Stain & Odor Remover – 1.0 Gal

Simple Green Bio Dog Stain & Odor Remover - 1.0 Gal

  • 1 Gal

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Product Details

Specifications

Details
Package Weight 8.875 lbs.
MFG Brand Name Simple Green
Supplier Product Type/Category Pet Products, Stain and Odor Eliminator
Aerosol Propellant No
Ammonia Neutralizer No

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susan
Emmy
AliO

20. Nature’s Miracle Stain & Odor Remover (32 oz)

Nature's Miracle Stain & Odor Remover (32 oz)

  • Works to remove pet stains and odors
  • Freshens with a light citrus scent
  • Bacteria-based formula produces enzymes when it comes in contact with Bio material to help remove organic stains and odors

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Rural King

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Details
Weight 2 lb

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Conclusion

The enzymatic cleaner for dog urine is an effective way to remove the odor of dog urine from your home. The cleaner contains enzymes that break down the proteins in the urine, which is what causes the odor.

The cleaner is safe to use around children and pets, and it is also biodegradable.

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